User GuideΒΆ This guide introduces the main concepts in Codeine, via various worked examples. Contents: Basic usage Counting Sampling Enumeration Adding constraints Forbidden motifs Max homopolymer Fixed codons Combining constraints Sequence contexts Mutation spaces Creating a mutation space Distance constraints Constraining free positions Enumerating & sampling variants Inherited constraints Translation tables Choosing a translation table Custom tables RNA tables Available tables Codon weights Species-specific weights Custom weights